Chapter 11: Problem 14
Distinguish between (a) unidirectional and bidirectional synthesis, and (b) continuous and discontinuous synthesis of DNA.
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Chapter 11: Problem 14
Distinguish between (a) unidirectional and bidirectional synthesis, and (b) continuous and discontinuous synthesis of DNA.
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In \(1994,\) telomerase activity was discovered in human cancer cell lines. Although telomerase is not active in human somatic tissue, this discovery indicated that humans do contain the genes for telomerase proteins and telomerase RNA. since inappropriate activation of telomerase may contribute to cancer, why do you think the genes coding for this enzyme have been maintained in the human genome throughout evolution? Are there any types of human body cells where telomerase activation would be advantageous or even necessary? Explain.
Review the Chapter Concepts list on \(\mathrm{p} .295 .\) These are concerned with the replication and synthesis of DNA. Write a short essay that distinguishes between the terms replication and synthesis, as applied to DNA. Which of the two is most closely allied with the field of biochemistry?
What is the end replication problem?
Summarize and compare the properties of DNA polymerase I II, and III.
What are the replication origins in bacteria, yeast, and mammalian cells?
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