Chapter 16: Problem 9
What reactions in animal cells are required to generate long-chain saturated and unsaturated fatty acids from palmitate?
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Chapter 16: Problem 9
What reactions in animal cells are required to generate long-chain saturated and unsaturated fatty acids from palmitate?
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Compare and contrast the fatty acid degradation and fatty acid synthesis pathways in eukaryotic cells.
What are the four types of chemical reactions needed in the fatty acid synthesis pathway to add a \(\mathrm{C}_{2}\) acetyl group to the growing hydrocarbon chain? Include the names of the cytosolic enzyme subunits that catalyze each reaction.
Describe the pathway by which excess acetyl-CoA produced by the pyruvate dehydrogenase reaction in the mitochondrial matrix of liver cells is used to synthesize triacylglycerols that are exported into the blood as VLDL particles. Specifically, what key enzymes are required, and how is flux through this carbohydrate \(\rightarrow\) lipid pathway maintained under conditions of high energy charge?
Sphingomyelin contains a phosphate in its head group, so is it a phospholipid or a sphingolipid? Where does the phosphate group come from in sphingomyelin?
What are the primary metabolic fates of liver cholesterol?
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