Chapter 24: Problem 8
Give an example of respiratory alkalosis and one of metabolic acidosis. In each case, explain how your example illustrates that type of acid-base disturbance.
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Chapter 24: Problem 8
Give an example of respiratory alkalosis and one of metabolic acidosis. In each case, explain how your example illustrates that type of acid-base disturbance.
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A mong related species (e.g- vertebrates), there is often a positive correlation between the oxygen-carrying capacity of blood and the height of the carbon dioxide equilibrium curve (the total carbon dioxide concentration at high \(\mathrm{CO}_{2}\) partial pressures). Why?
When fishing boats pull trawling nets through the water, many fish avoid being caught by vigorously swimming away. Others, after vigorous escape swimming, get caught, but later are released because they are not of legal size or are not the species desired. Fish that escape or are released sometimes die anyway. The accumulation of lactic acid from anaerobic work in such fish seems in certain cases to be a key factor in their deaths. How could a large lactic acid accumulation in a fish interfere with its ability to obtain enough \(\mathrm{O}_{2}\) to survive?
As noted in this chapter, respiratory pigments that are dissolved in the blood plasma usually have very high molecular weights. The statement has been made that in animals with dissolved respiratory pigments, "the polymerization of unit respiratorypigment molecules into high-molecular-weight polymers allows the blood solution to have a high oxygen-carrying capacity without having its osmotic pressure boosted to high levels by the presence of the respiratory pigment." Explain. (Hint: Review in Chapter 5 how dissolved entities affect the colligative properties of solutions.)
In most species of mammals, the \(\mathrm{O}_{2}\) affinity of a fetus's blood hemoglobin is greater than that of its mother's blood hemoglobin. However, mammal species are not all the same in the mechanism that causes the affinities to be different. Specify three distinct mechanisms for the difference in affinity between fetal and maternal blood hemoglobin. Recall from Chapter 1 that François Jacob argued that evolution is analogous to tinkering rather than engineering. Considering the mechanism of the fetal- maternal difference in \(\mathrm{O}_{2}\) affinity, would you say that the evolution of the mechanism provides evidence for Jacob's argument? Explain.
Outline the ways in which mammalian hemoglobin simultaneously plays important roles in \(\mathrm{O}_{2}\) transport, \(\mathrm{CO}_{2}\) transport, and control of blood pH.
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